ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ig heavy chain V region 5-84

Intramolecular
Cysteine 41 and cysteine 115
A redox-regulated disulphide may form within Ig heavy chain V region 5-84 between cysteines 41 and 115 (22 and 96 respectively in this structure).

Details

Redox score ?
80
PDB code
1mqk
Structure name
crystal structure of the unliganded fv-fragment of the anti-cytochrome c oxidase antibody 7e2
Structure deposition date
2002-09-16
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
P18525
Residue number A
41
Residue number B
115
Peptide name
Ig heavy chain V region 5-84

Ligandability

Cysteine 41 of Ig heavy chain V region 5-84

Cysteine 115 of Ig heavy chain V region 5-84

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